Azzota C-1010-10mg ABT-737 - 10 mg Solid Powder

ABT-737 - 10 mg Solid Powder

ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM, respectively. ABT-737 has no inhibition observed against Mcl-1, Bcl-B or Bfl-1.

Targets: PARP

Synonym: ABT 737; ABT-737; ABT737

Chemical Name/IUPAC:(R)-4-(4-((4'-chloro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-(dimethylamino)-1-(phenylthio)butan-2-yl)amino)-3-nitrophenyl)sulfonyl)benzamide

Technical Data

• Product Name: ABT-737
• Chemical Formula: C42H45ClN6O5S2
• Molecular Weight: 813.43
• CAS#: 852808-04-9
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for six months, or -20oC for three years
• Weight - 10mg