Azzota C-1004-50mg A-1210477 - 50mg Solid Powder

A-1210477 - 50mg Solid Powder

A-1210477 is a potent and selective MCL-1 inhibitor. A-1210477 disrupted the interaction between MCL-1 and pro-apoptotic BIM, inducing the hallmarks of apoptosis in MCL-1-dependent multiple myeloma and non-small cell lung cancer cell lines.

Targets: MCL-1

Synonym: A-1210477; A1210477; A 1210477 Chemical Name/IUPAC:7-(5-((4-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid

Technical Data

• Product Name: A-1210477
• Chemical Formula: C46H55N7O7S
• Molecular Weight: 850.05
• CAS#: 1668553-26-1
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for months, or -20ºC for three years
• Weight - 50mg